Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 2/20 | 0.43 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797069 | 0.87 | SMARCA2 (0.38) | SMARCA2SMARCA4 | |
| SCHEMBL30796719 | 0.86 | SMARCA2 (0.43) | TRPC3TRPC7SMN1; SMN2CYP2C19GRIN2B | |
| SCHEMBL29942646 | 0.85 | SMARCA2 (0.38) | SMN1; SMN2CYP2C19GRIN2BNPC1RAB9A | |
| SCHEMBL30797119 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2C19GRIN2BNPC1RAB9A | |
| SCHEMBL30796771 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2C19GRIN2BNPC1RAB9A | |
| SCHEMBL30796727 | 0.80 | SMN1; SMN2 (0.48) | TRPC3TRPC7SMN1; SMN2CYP2C19GRIN2B | |
| SCHEMBL30796962 | 0.79 | PRMT5 (0.50) | SMN1; SMN2CYP2C19GRIN2BNPC1RAB9A | |
| SCHEMBL23301277 | 0.79 | LNPEP (0.43) | SMN1; SMN2CYP2C19GRIN2BNPC1RAB9A | |
| SCHEMBL30796273 | 0.78 | HDAC1 (0.50) | SMN1; SMN2CYP2C19GRIN2BNPC1RAB9A | |
| SCHEMBL29221603 | 0.78 | HDAC1 (0.50) | SMN1; SMN2CYP2C19GRIN2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539849-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |