Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30796704 | 0.84 | SMARCA2 (0.67) | SMARCA2SMARCA4 | |
| SCHEMBL29943975 | 0.83 | NPC1 (0.54) | SMARCA2SMARCA4GAACNR1TP53 | |
| SCHEMBL23630487 | 0.83 | NPC1 (0.54) | SMARCA2SMARCA4GAACNR1TP53 | |
| SCHEMBL30796186 | 0.81 | OPRM1 (0.52) | SMARCA2SMARCA4MEN1KMT2AOPRM1 | |
| SCHEMBL23303143 | 0.81 | OPRM1 (0.52) | SMARCA2SMARCA4MEN1KMT2AOPRM1 | |
| SCHEMBL29910687 | 0.81 | OPRM1 (0.52) | SMARCA2SMARCA4MEN1KMT2AOPRM1 | |
| SCHEMBL23304144 | 0.80 | SMARCA2 (0.43) | SMARCA2SMARCA4CNR1OPRM1 | |
| SCHEMBL29910620 | 0.80 | SMARCA2 (0.43) | SMARCA2SMARCA4CNR1OPRM1 | |
| SCHEMBL23301218 | 0.79 | KDM4E (0.43) | SMARCA2SMARCA4MAPTALDH1A1KDM4E | |
| SCHEMBL29942586 | 0.79 | KDM4E (0.43) | SMARCA2SMARCA4MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539849-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |