Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 6/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 6/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30796186 | 1.00 | OPRM1 (0.52) | OPRM1SMARCA2SMARCA4OPRD1OPRK1 | |
| SCHEMBL29910687 | 1.00 | OPRM1 (0.52) | OPRM1SMARCA2SMARCA4OPRD1OPRK1 | |
| SCHEMBL27456634 | 1.00 | OPRM1 (0.52) | OPRM1SMARCA2SMARCA4OPRD1OPRK1 | |
| SCHEMBL27456475 | 0.95 | OPRM1 (0.47) | OPRM1SMARCA2SMARCA4OPRD1OPRK1 | |
| SCHEMBL29910569 | 0.85 | SMARCA2 (0.43) | OPRM1SMARCA2SMARCA4OPRD1OPRK1 | |
| SCHEMBL23304101 | 0.85 | SMARCA2 (0.43) | OPRM1SMARCA2SMARCA4OPRD1OPRK1 | |
| SCHEMBL29910555 | 0.83 | SMARCA2 (0.41) | OPRM1SMARCA2SMARCA4 | |
| SCHEMBL23304039 | 0.83 | SMARCA2 (0.41) | OPRM1SMARCA2SMARCA4 | |
| SCHEMBL30796963 | 0.81 | SMARCA2 (0.46) | OPRM1SMARCA2SMARCA4MEN1KMT2A | |
| SCHEMBL26556828 | 0.78 | SMARCA2 (0.48) | SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002367-A1 | BIFUNCTIONAL COMPOUNDS | C4 THERAPEUTICS, INC. | 2023-01-05 | — | — | US | disclosed |
| EP-4054724-A1 | BIFUNCTIONAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2022-09-14 | — | — | EP | disclosed |
| WO-2021086785-A1 | BIFUNCTIONAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002367-A1 | BIFUNCTIONAL COMPOUNDS | ITCH, EGFR, MUC1 | OPRM1 1828/4885SMARCA2 3260/4885SMARCA4 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.