Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 6/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.30 |
| ▸ | DLK1 | P80370 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797146 | 0.87 | TRPC3 (0.43) | SMARCA2SMARCA4 | |
| SCHEMBL27458085 | 0.74 | SMARCA2 (0.48) | SMARCA2SMARCA4 | |
| SCHEMBL21438564 | 0.73 | SMARCA2 (0.51) | SMARCA2SMARCA4 | |
| SCHEMBL27458561 | 0.73 | SMARCA2 (0.59) | SMARCA2SMARCA4 | |
| SCHEMBL30796712 | 0.73 | SMARCA2 (0.59) | SMARCA2SMARCA4 | |
| SCHEMBL22776733 | 0.72 | SMARCA2 (0.34) | SMARCA2SMARCA4SLC6A7TRPC6 | |
| SCHEMBL28942502 | 0.72 | SMARCA2 (0.34) | SMARCA2SMARCA4SLC6A7TRPC6 | |
| SCHEMBL30796207 | 0.72 | SMARCA2 (0.51) | SMARCA2SMARCA4 | |
| SCHEMBL30796288 | 0.71 | SMARCA2 (0.47) | SMARCA2SMARCA4MAP3K12 | |
| SCHEMBL27458407 | 0.71 | SMARCA2 (0.49) | SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539849-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |