Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797103 | 0.89 | CNR1 (0.43) | CNR1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6688374 | 0.83 | HDAC3 (0.51) | NPC1RAB9ASMN1; SMN2MITFJAK3 | |
| SCHEMBL23747576 | 0.79 | RAB9A (0.61) | CNR1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6690096 | 0.75 | MAOA (0.53) | CNR1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10939812 | 0.75 | CNR1 (0.70) | CNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15420541 | 0.75 | HDAC3 (0.42) | NPC1RAB9ASMN1; SMN2MITFJAK3 | |
| SCHEMBL17912894 | 0.73 | CNR1 (0.63) | CNR1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4708584 | 0.73 | CNR1 (0.50) | CNR1NPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL10802920 | 0.73 | CNR1 (0.63) | CNR1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8244860 | 0.73 | CNR1 (0.63) | CNR1NPC1RAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |