SCHEMBL30798076

SCHEMBL30798076

CC(C)(C)OC(=O)N1Cc2cn(-c3ccnc(Cl)n3)nc2C1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 2/20 0.42
MAPT P10636 2/20 0.39
POLB P06746 1/20 0.39
ESR2 Q92731 1/20 0.38
GPR119 Q8TDV5 3/20 0.38
MAPK1 P28482 1/20 0.38
DDB1 Q16531 1/20 0.37
CRBN Q96SW2 1/20 0.37
HDAC1 Q13547 1/20 0.37
NR1H2 P55055 2/20 0.36
EIF2AK4 Q9P2K8 1/20 0.36
PDK2 Q15119 1/20 0.36
SLC6A9 P48067 2/20 0.36
ROCK2 O75116 1/20 0.36
KCNH2 Q12809 1/20 0.36
PIK3CA P42336 1/20 0.35
MTOR P42345 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15159353 0.85 SLC34A1 (0.43) SLC34A1MAPTGPR119MAPK1DDB1
SCHEMBL30798207 0.84 SLC34A1 (0.41) SLC34A1MAPTPOLBESR2GPR119
SCHEMBL20075219 0.80 SLC34A1 (0.50) SLC34A1MAPTPOLBESR2GPR119
SCHEMBL30798307 0.79 SLC34A1 (0.41) SLC34A1ESR2GPR119PDK2SLC6A9
SCHEMBL30798259 0.78 GPR119 (0.47) POLBGPR119EIF2AK4
SCHEMBL30798134 0.75 SLC34A1 (0.40) SLC34A1MAPTPOLBESR2GPR119
SCHEMBL1320120 0.75 GPR119 (0.56) POLBGPR119
SCHEMBL15875047 0.74 DDB1 (0.53) MAPTPOLBESR2GPR119MAPK1
SCHEMBL23015352 0.74 HDAC1 (0.45) SLC34A1ESR2GPR119MAPK1HDAC1
SCHEMBL17202429 0.74 GRM5 (0.49) SLC34A1POLBESR2GPR119HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024028795-A1 HETEROBICYCLIC COMPOUNDS AS ORAL GLP1R AGONISTS ZYDUS LIFESCIENCES LIMITED (IN) 2024-02-08 WO disclosed