Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798076 | 0.84 | SLC34A1 (0.42) | SLC34A1ESR2MAPK1SLC6A9KCNH2 | |
| SCHEMBL20075219 | 0.80 | SLC34A1 (0.50) | SLC34A1ESR2SLC6A9KCNH2HDAC1 | |
| SCHEMBL30798134 | 0.80 | SLC34A1 (0.40) | SLC34A1ESR2SLC6A9KCNH2C5AR1 | |
| SCHEMBL15159353 | 0.78 | SLC34A1 (0.43) | SLC34A1MAPK1SLC6A9KCNH2HDAC1 | |
| SCHEMBL31186180 | 0.77 | MAPT (0.48) | SLC34A1ESR2MAPK1C5AR1MAPT | |
| SCHEMBL30798121 | 0.77 | HTR3E (0.43) | ESR2MAPK1POLBGPR119NAMPT | |
| SCHEMBL868119 | 0.76 | ABHD6 (0.63) | ABHD6ESR2MAPK1HDAC1MAPT | |
| SCHEMBL30419519 | 0.76 | ABHD6 (0.63) | ABHD6ESR2MAPK1HDAC1MAPT | |
| SCHEMBL23015352 | 0.75 | HDAC1 (0.45) | SLC34A1ESR2MAPK1SLC6A9HDAC1 | |
| SCHEMBL17202429 | 0.75 | GRM5 (0.49) | SLC34A1ESR2SLC6A9KCNH2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028795-A1 | HETEROBICYCLIC COMPOUNDS AS ORAL GLP1R AGONISTS | ZYDUS LIFESCIENCES LIMITED (IN) | 2024-02-08 | — | — | WO | disclosed |