Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798187 | 0.88 | GPR119 (0.42) | SLC34A1GPR119SLC6A9KCNH2 | |
| SCHEMBL30798361 | 0.83 | GPR119 (0.41) | GLP1RCYP3A4CYP3A5KDM5AKDM5B | |
| SCHEMBL30798346 | 0.83 | GPR119 (0.41) | GLP1RCYP3A4CYP3A5KDM5AKDM5B | |
| SCHEMBL22391741 | 0.81 | GPR119 (0.50) | GLP1RCYP3A4CYP3A5KDM5AKDM5B | |
| SCHEMBL30798076 | 0.79 | SLC34A1 (0.42) | SLC34A1GPR119SLC6A9KCNH2PDK2 | |
| SCHEMBL30798193 | 0.77 | KDM5A (0.37) | GLP1RKDM5AKDM5BKCNH2PTGER1 | |
| SCHEMBL25322361 | 0.77 | ESR2 (0.45) | CYP3A4CYP3A5GPR119MKNK1ESR2 | |
| SCHEMBL30798079 | 0.76 | SLC34A1 (0.43) | SLC34A1GLP1RGPR119SLC6A9KCNH2 | |
| SCHEMBL15159353 | 0.76 | SLC34A1 (0.43) | SLC34A1CYP3A4GPR119SLC6A9KCNH2 | |
| SCHEMBL22391791 | 0.75 | TRPV3 (0.47) | GLP1RCYP3A4CYP3A5GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028795-A1 | HETEROBICYCLIC COMPOUNDS AS ORAL GLP1R AGONISTS | ZYDUS LIFESCIENCES LIMITED (IN) | 2024-02-08 | — | — | WO | disclosed |