SCHEMBL30798232

SCHEMBL30798232

CC(C)(C)OC(=O)N1CC2=C(C1)CN(c1cccc(OCc3ccc(Cl)cc3F)n1)C2

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24320615 0.89 GLP1R (0.51) GLP1R
SCHEMBL30209272 0.89 GLP1R (0.51) GLP1R
SCHEMBL30797977 0.87 GLP1R (0.47) GLP1R
SCHEMBL30798346 0.86 GPR119 (0.41) GLP1R
SCHEMBL30798361 0.86 GPR119 (0.41) GLP1R
SCHEMBL22391653 0.84 MKNK1 (0.43) GLP1R
SCHEMBL24320732 0.81 GLP1R (0.54) GLP1R
SCHEMBL30468802 0.80 GLP1R (0.48) GLP1R
SCHEMBL20266522 0.79 GLP1R (0.58) GLP1R
SCHEMBL22391822 0.79 CYP3A4 (0.44) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024028795-A1 HETEROBICYCLIC COMPOUNDS AS ORAL GLP1R AGONISTS ZYDUS LIFESCIENCES LIMITED (IN) 2024-02-08 WO disclosed