Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798361 | 1.00 | GPR119 (0.41) | GPR119CYP3A4CYP3A5KDM5AKDM5B | |
| SCHEMBL22391741 | 0.89 | GPR119 (0.50) | GPR119CYP3A4CYP3A5KDM5AKDM5B | |
| SCHEMBL30798232 | 0.86 | GLP1R (0.45) | GLP1R | |
| SCHEMBL30798307 | 0.83 | SLC34A1 (0.41) | GPR119CYP3A4CYP3A5KDM5AKDM5B | |
| SCHEMBL28546320 | 0.81 | MAP4K4 (0.47) | GPR119EIF2AK4GLP1R | |
| SCHEMBL30269669 | 0.81 | MAP4K4 (0.47) | GPR119EIF2AK4GLP1R | |
| SCHEMBL30798049 | 0.79 | KDM5A (0.40) | KDM5AKDM5BRXRAGRIN1GRIN2B | |
| SCHEMBL22391791 | 0.79 | TRPV3 (0.47) | GPR119CYP3A4CYP3A5USP30GLP1R | |
| SCHEMBL30209321 | 0.79 | TRPV3 (0.47) | GPR119CYP3A4CYP3A5USP30GLP1R | |
| SCHEMBL22391815 | 0.77 | GRM1 (0.48) | GPR119MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028795-A1 | HETEROBICYCLIC COMPOUNDS AS ORAL GLP1R AGONISTS | ZYDUS LIFESCIENCES LIMITED (IN) | 2024-02-08 | — | — | WO | disclosed |