Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 2/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171856 | 1.00 | MMP12 (0.45) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL225931 | 0.77 | MMP12 (0.73) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL29919790 | 0.77 | MMP12 (0.73) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL5046499 | 0.76 | MMP12 (0.45) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL3997475 | 0.75 | RAB9A (0.45) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL30799511 | 0.75 | RAB9A (0.45) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL4606421 | 0.74 | MMP12 (0.47) | MMP12KDM4EALDH1A1HDAC6QPCT | |
| SCHEMBL6364797 | 0.74 | MMP12 (0.46) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL3162533 | 0.74 | MMP12 (0.50) | MMP12MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL1875326 | 0.73 | MMP12 (0.46) | MMP12KDM4EALDH1A1CYP3A4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2024051354-A1 | BENZIMIDAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州沪云新药研发股份有限公司 | 2024-03-14 | — | — | WO | disclosed |