Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | CBFB | Q13951 | 2/20 | 0.42 |
| ▸ | RUNX1 | Q01196 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SCN4A | P35499 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993036 | 0.87 | MMP12 (0.42) | MMP12CBFBRUNX1KIF11KDM4E | |
| SCHEMBL1266231 | 0.86 | MMP12 (0.62) | MMP12CBFBRUNX1KIF11KDM4E | |
| SCHEMBL31465271 | 0.86 | MMP12 (0.62) | MMP12CBFBRUNX1KIF11KDM4E | |
| SCHEMBL2105843 | 0.79 | MMP12 (0.45) | MMP12KDM4EBLMNPC1RAB9A | |
| SCHEMBL23636198 | 0.78 | MMP12 (0.55) | MMP12CBFBRUNX1KDM4EIDO1 | |
| SCHEMBL30468089 | 0.78 | MMP12 (0.55) | MMP12CBFBRUNX1KDM4EIDO1 | |
| SCHEMBL225931 | 0.77 | MMP12 (0.73) | MMP12KDM4EBLMNPC1RAB9A | |
| SCHEMBL29919790 | 0.77 | MMP12 (0.73) | MMP12KDM4EBLMNPC1RAB9A | |
| SCHEMBL30798705 | 0.76 | MMP12 (0.45) | MMP12KDM4EBLMNPC1RAB9A | |
| SCHEMBL29171856 | 0.76 | MMP12 (0.45) | MMP12KDM4EBLMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296925-A1 | METALLOENZYME INHIBITOR COMPOUNDS | CORXEL PHARMACEUTICALS HONG KONG LTD (HK) | 2025-09-25 | — | — | US | disclosed |
| US-12358893-B2 | Metalloenzyme inhibitor compounds | CORXEL PHARMACEUTICALS HONG KONG LIMITED (HK) | 2025-07-15 | — | — | US | disclosed |
| CN-118063453-B | Benzimidazole derivative, preparation method and application thereof, and agricultural bactericide | 南京吉星生物技术开发有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-119060053-A | Nuclear receptor binding SET structural domain protein 2/3 inhibitor, and pharmaceutical composition and application thereof | 深圳众格生物科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| US-20240230952-A1 | LAMINATE AND METHOD FOR MANUFACTURING LAMINATE | FUJIFILM CORPORATION (JP) | 2024-07-11 | — | — | US | disclosed |
| US-20240230952-A1 | LAMINATE AND METHOD FOR MANUFACTURING LAMINATE | FUJIFILM CORPORATION (JP) | 2024-07-11 | — | — | US | disclosed |
| CN-118063453-A | Benzimidazole derivative, preparation method and application thereof, and agricultural bactericide | 南京吉星生物技术开发有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20240027897-A1 | LAMINATE AND MANUFACTURING METHOD OF LAMINATE | FUJIFILM CORPORATION (JP) | 2024-01-25 | — | — | US | disclosed |
| US-20240027897-A1 | LAMINATE AND MANUFACTURING METHOD OF LAMINATE | FUJIFILM CORPORATION (JP) | 2024-01-25 | — | — | US | disclosed |
| EP-3908319-B1 | METALLOENZYME INHIBITOR COMPOUNDS | JI XING PHARMACEUTICALS HONG KONG LTD (HK) | 2023-10-18 | — | — | EP | disclosed |
| US-7432378-B2 | Benzoimidazole compounds | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-10-07 | — | — | US | disclosed |
| US-20070203210-A1 | Thiazolyl-benzimidazoles | BOYLAN JOHN FREDERICK | 2007-08-30 | — | — | US | disclosed |
| US-20070203210-A1 | Thiazolyl-benzimidazoles | BOYLAN JOHN FREDERICK | 2007-08-30 | — | — | US | disclosed |
| US-20050070550-A1 | Benzoimidazole compounds | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-31 | — | — | US | disclosed |
| EP-0844998-B1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| US-20030027842-A1 | Halogenobenzimidazoles | ASSMANN LUTZ (DE) | 2003-02-06 | — | — | US | disclosed |
| US-6387939-B1 | PLANT SAFENING AGNETS; FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-14 | — | — | US | disclosed |
| US-6268508-B1 | FOR CROP PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-31 | — | — | US | disclosed |
| US-6160001-A | Halobenzimidazoles and their use as microbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| US-6020354-A | FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070550-A1 | Benzoimidazole compounds | HRH4, HRH3, BRD4 | MMP12 562/4885CBFB 1180/4885RUNX1 1980/4885 |
| US-12358893-B2 | Metalloenzyme inhibitor compounds | SOD1, RNASE1, FECH | MMP12 15/4885CBFB 1693/4885RUNX1 1529/4885 |
| US-20070203210-A1 | Thiazolyl-benzimidazoles | CYP3A7, CYP2C19, CYP3A5 | MMP12 3994/4885CBFB 3304/4885RUNX1 2399/4885 |
| US-20250296925-A1 | METALLOENZYME INHIBITOR COMPOUNDS | SOD1, RNASE1, FECH | MMP12 15/4885CBFB 1693/4885RUNX1 1529/4885 |
| US-20030027842-A1 | Halogenobenzimidazoles | MSR1, MRPS23, CBR1 | MMP12 1483/4885CBFB 1508/4885RUNX1 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.