Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 8/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DNA2 | P51530 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003986 | 1.00 | TDP1 (0.48) | TDP1ALDH1A1TSHRMAPK1VCAM1 | |
| SCHEMBL3920360 | 0.86 | TDP1 (0.48) | TDP1ALDH1A1TSHRMAPK1VCAM1 | |
| Ethoxycarbonyl Group SCHEMBL28461257 | 0.84 | TDP1 (0.36) | TDP1ALDH1A1VCAM1FBP1P2RX7 | |
| SCHEMBL15845436 | 0.80 | ALDH1A1 (0.43) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31488147 | 0.79 | ALDH1A1 (0.44) | TDP1ALDH1A1TSHRMAPK1P2RX7 | |
| SCHEMBL2768608 | 0.79 | ALDH1A1 (0.44) | TDP1ALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL22532255 | 0.79 | CASP6 (0.50) | TDP1ALDH1A1TSHRMAPK1VCAM1 | |
| SCHEMBL29764388 | 0.79 | ALDH1A1 (0.44) | TDP1ALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL30799056 | 0.79 | CASP6 (0.50) | TDP1ALDH1A1TSHRMAPK1VCAM1 | |
| SCHEMBL6537811 | 0.78 | TDP1 (0.44) | TDP1ALDH1A1TSHRMAPK1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634155-A1 | RBM39 SULFONAMIDE INHIBITORS | Recursion Pharmaceuticals, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4573088-A1 | HETEROCYCLE RBM39 MODULATORS | Recursion Pharmaceuticals, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024129634-A1 | RBM39 SULFONAMIDE INHIBITORS | RECURSION PHARMACEUTICALS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024039689-A1 | HETEROCYCLE RBM39 MODULATORS | RECURSION PHARMACEUTICALS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |