SCHEMBL30799248

SCHEMBL30799248

Cc1cc(N)c2c(ccn2COCC[Si](C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 5/20 0.37
PDE10A Q9Y233 4/20 0.32
KLKB1 P03952 1/20 0.32
NPC1 O15118 1/20 0.32
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
DUT P33316 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30018075 0.82 DGAT1 (0.38) DGAT1PDE10ANPC1HTR2AHTR2C
SCHEMBL19204030 0.78 DGAT1 (0.40) DGAT1PDE10AKLKB1NPC1DUT
SCHEMBL28840671 0.78 HTR2C (0.48) DGAT1PDE10ANPC1HTR2AHTR2C
SCHEMBL29925168 0.78 HTR2C (0.48) DGAT1PDE10ANPC1HTR2AHTR2C
SCHEMBL26728337 0.75 HTR2A (0.48) DGAT1PDE10AKLKB1HTR2AHTR2C
SCHEMBL4503124 0.75 ADRA2A (0.43) DGAT1PDE10AKLKB1DUT
SCHEMBL31358047 0.75 DGAT1 (0.41) DGAT1HTR2AHTR2C
SCHEMBL16192744 0.75 DGAT1 (0.37) DGAT1HTR2AHTR2CDUT
SCHEMBL22778051 0.74 DGAT1 (0.36) DGAT1NPC1HTR2AHTR2CDUT
SCHEMBL29714404 0.74 DGAT1 (0.36) DGAT1NPC1HTR2AHTR2CDUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573088-A1 HETEROCYCLE RBM39 MODULATORS Recursion Pharmaceuticals, Inc. (US) 2025-06-25 EP disclosed
WO-2024039689-A1 HETEROCYCLE RBM39 MODULATORS RECURSION PHARMACEUTICALS, INC. (US) 2024-02-22 WO disclosed