SCHEMBL30799287

SCHEMBL30799287

Cc1cc(N)c2c(c1)c(C#N)cn2COCC[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.32
DGAT1 O75907 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
POLB P06746 1/20 0.30
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27174942 1.00 L3MBTL1 (0.32) L3MBTL1DGAT1LMNAHTTSMN1; SMN2
SCHEMBL27174910 0.81 MAPT (0.31) TDP1POLB
SCHEMBL31482767 0.81 MAPT (0.31) TDP1POLB
SCHEMBL13961214 0.76 DGAT1 (0.31) DGAT1HTTSMN1; SMN2TDP1POLB
SCHEMBL2423387 0.76 DGAT1 (0.33) DGAT1HTTSMN1; SMN2TDP1POLB
SCHEMBL22803875 0.75 POLB (0.37) L3MBTL1LMNAHTTSMN1; SMN2TDP1
SCHEMBL5253803 0.74 NPC1 (0.34) KDM1A
SCHEMBL2431756 0.73 KDM4E (0.33)
SCHEMBL2432945 0.73 KDM4E (0.32) POLB
SCHEMBL30799248 0.73 DGAT1 (0.37) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573088-A1 HETEROCYCLE RBM39 MODULATORS Recursion Pharmaceuticals, Inc. (US) 2025-06-25 EP disclosed
CN-119630658-A Heterocyclic RBM39 modulators 递归医药公司 2025-03-14 CN disclosed
WO-2024039689-A1 HETEROCYCLE RBM39 MODULATORS RECURSION PHARMACEUTICALS, INC. (US) 2024-02-22 WO disclosed