Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16237129 | 0.73 | ATM (0.38) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL31180653 | 0.69 | BRD4 (0.44) | BRD4 | |
| SCHEMBL18393939 | 0.69 | ALDH1A1 (0.31) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL31180683 | 0.69 | BRD4 (0.33) | BRD4ALDH1A1TDP1 | |
| SCHEMBL21266558 | 0.68 | RAB9A (0.61) | ALDH1A1TDP1 | |
| SCHEMBL16236354 | 0.68 | TDP1 (0.44) | TDP1 | |
| SCHEMBL16236979 | 0.68 | TDP1 (0.59) | ALDH1A1TDP1 | |
| SCHEMBL31180718 | 0.68 | BRD4 (0.39) | BRD4HSD17B10 | |
| SCHEMBL11073134 | 0.66 | — | — | |
| SCHEMBL3012642 | 0.66 | KMT2A (0.44) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117700408-B | Novel protein tyrosine phosphatase SHP-1 inhibitor and application thereof | 中国药科大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-117700408-A | Novel protein tyrosine phosphatase SHP-1 inhibitor and application thereof | 中国药科大学 | 2024-03-15 | — | — | CN | disclosed |