Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28102167 | 0.79 | ATM (0.38) | ALDH1A1GAAATMLMNAMEN1 | |
| SCHEMBL28219865 | 0.70 | — | — | |
| SCHEMBL7268279 | 0.69 | ALDH1A1 (0.43) | ALDH1A1GAAATMLMNAMEN1 | |
| SCHEMBL28070758 | 0.68 | ALDH1A1 (0.37) | ALDH1A1GAAATMLMNAMEN1 | |
| Hydrochloric Acid SCHEMBL11841772 | 0.65 | — | — | |
| SCHEMBL30799193 | 0.65 | FBP1 (0.47) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL28065581 | 0.64 | — | — | |
| SCHEMBL28128640 | 0.62 | — | — | |
| SCHEMBL9594434 | 0.61 | ALDH1A1 (0.38) | ALDH1A1GAAATMLMNAMEN1 | |
| SCHEMBL30799058 | 0.61 | ALDH1A1 (0.32) | ALDH1A1MAPTFAAHMGLLEGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551035-A | Nitrogen-containing trisubstituted olefin compound and preparation method and application thereof | 华南师范大学 | 2024-02-13 | — | — | CN | disclosed |