Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30799359 | 0.79 | ALDH1A1 (0.38) | ATMLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28128640 | 0.77 | — | — | |
| SCHEMBL28452970 | 0.72 | FAAH (0.35) | ATMLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL1371556 | 0.71 | — | — | |
| SCHEMBL28070758 | 0.69 | ALDH1A1 (0.37) | ATMLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9584008 | 0.67 | FAAH (0.51) | ATMLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL19068319 | 0.67 | FAAH (0.36) | ATMLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28219865 | 0.67 | — | — | |
| SCHEMBL83387 | 0.66 | MGLL (0.50) | LMNAALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL7268279 | 0.66 | ALDH1A1 (0.43) | ATMLMNAALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585562-B | 1- (benzofuran -5- bases) -3- aryl -2- (triazol-1-yl) propenone and its application as anticarcinogen | 湖南大学 | 2018-09-21 | — | — | CN | disclosed |
| CN-105859696-B | 1- benzofuranols ether -3- phenyl -2- (1,2,4- triazol-1-yl) -2- propenone and its application | 湖南大学 | 2018-05-25 | — | — | CN | disclosed |
| CN-104610236-B | The preparation and application of furans amphyl containing triazolyl | 宁波工程学院 | 2017-08-04 | — | — | CN | disclosed |
| CN-104370893-B | 1-(7-propoxybenzofuryl-5-yl)-3-(2-chlorophenyl)-2-(1,2,4-triazolyl-1-yl)acrylketone | 湖南大学 | 2017-04-12 | — | — | CN | disclosed |
| CN-104387373-B | 1-(7-propoxy benzofuran-5-group)-3-(2-methoxyl phenyl)-2-(1,2,4-triazole-1- group)acrylketone | 湖南大学 | 2017-02-15 | — | — | CN | disclosed |
| CN-104496973-B | Benzofuranol propenone derivatives is as the application of insecticide | 邵阳学院 | 2016-11-30 | — | — | CN | disclosed |