Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | CCKAR | P32238 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 3/20 | 0.51 |
| ▸ | NPY2R | P49146 | 3/20 | 0.51 |
| ▸ | NPY4R | P50391 | 3/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30799936 | 0.94 | UTS2R (0.57) | GHSRERBB2ECE1MMP9MMP8 | |
| SCHEMBL31074343 | 0.92 | ERAP2 (0.59) | ECE1ERAP2ACE | |
| SCHEMBL30799518 | 0.90 | GHSR (0.63) | GHSR | |
| SCHEMBL31483390 | 0.89 | ACE (0.56) | ECE1ERAP2UTS2RACE | |
| SCHEMBL30799736 | 0.89 | KDM4E (0.57) | GHSRECE1NPY1RNPY2RNPY4R | |
| SCHEMBL30799943 | 0.89 | GHSR (0.59) | GHSRMMP2MMP9MMP8ERAP2 | |
| SCHEMBL31606519 | 0.88 | CCKBR (0.62) | CCKARCCKBRNPY1RNPY2RNPY4R | |
| SCHEMBL30291169 | 0.88 | ERAP2 (0.58) | GHSRECE1MMP1ERAP2NPY1R | |
| SCHEMBL31146519 | 0.88 | GHSR (0.61) | GHSRNPY1RNPY2RNPY4R | |
| SCHEMBL30799670 | 0.87 | GHSR (0.68) | GHSRECE1MMP9MMP8MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | GHSR 1194/4885ERBB2 1101/4885ECE1 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.