Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | GRB2 | P62993 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545820 | 0.90 | CTSC (0.33) | CTSC | |
| SCHEMBL13958826 | 0.88 | CTSC (0.34) | CTSC | |
| SCHEMBL22369842 | 0.88 | CTSC (0.34) | CTSC | |
| SCHEMBL30946342 | 0.87 | CNR2 (0.33) | CTSC | |
| SCHEMBL16362464 | 0.87 | CTSC (0.32) | CTSC | |
| SCHEMBL31388739 | 0.82 | GRB2 (0.36) | GRB2 | |
| SCHEMBL31388786 | 0.82 | GRB2 (0.37) | GRB2 | |
| SCHEMBL30987834 | 0.81 | — | — | |
| SCHEMBL3835494 | 0.80 | LTA4H (0.33) | — | |
| SCHEMBL3835499 | 0.80 | LTA4H (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | CTSC 732/4885GRB2 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.