SCHEMBL3835494

SCHEMBL3835494

CNC(=O)C(N)Cc1c[nH]cn1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.33
CYP3A4 P08684 1/20 0.33
SLC7A5 Q01650 1/20 0.33
NLN Q9BYT8 1/20 0.33
CSK P41240 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3835499 1.00 LTA4H (0.33) LTA4HCYP3A4SLC7A5NLNCSK
SCHEMBL1070087 0.86 CSK (0.33) CYP3A4SLC7A5NLNCSK
SCHEMBL11620101 0.86 CSK (0.45) CYP3A4SLC7A5NLNCSK
SCHEMBL4197031 0.86 CSK (0.45) CYP3A4SLC7A5NLNCSK
SCHEMBL1070085 0.86 CSK (0.33) CYP3A4SLC7A5NLNCSK
SCHEMBL24270549 0.85 SMN1; SMN2 (0.33) CSK
SCHEMBL13270040 0.85 OPRM1 (0.33)
SCHEMBL18210638 0.85 NLN (0.32) NLNCSK
SCHEMBL29616794 0.85 CSK (0.33) CSK
SCHEMBL14065661 0.85 SMN1; SMN2 (0.33) CSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2101728-A1 DISPERSION OF POLYAMINO ACIDS IN A CONTINUOUS LIPID PHASE Flamel Technologies (FR) 2009-09-23 EP claimed
WO-2008074871-A1 DISPERSION OF POLYAMINO ACIDS IN A CONTINUOUS LIPID PHASE FLAMEL TECHNOLOGIES (FR) 2008-06-26 WO claimed
US-20080152675-A1 Sustained release of drug in an aqueous phase containing at least one amphiphilic polymer; dispersion in a continuous lipid phase; water in oil emulsions; low viscosity for injection; aspartate-glutamate or aspartic-glutamic copolymers; biodrugs FLAMEL TECHNOLOGIES, S.A. (FR) 2008-06-26 US claimed
US-5409893-A Administering with platinum complexes BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) 1995-04-25 US claimed
US-20230065217-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS ESCIENT PHARMACEUTICALS, INC. 2023-03-02 US disclosed
WO-2021113851-A2 PEPTIDE DOCKING VEHICLE FOR TARGETED NUCLEIC ACID DELIVERY SIRNAOMICS, INC. (US) 2021-06-10 WO disclosed
US-9139614-B2 Modular linkers for conjugation of organic substances to substantially inorganic substances and methods of manufacture and use thereof THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-09-22 US disclosed
US-5409893-A Administering with platinum complexes BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) 1995-04-25 US disclosed
EP-0471709-B1 RUTHENIUM(III) COMPLEXES AS ANTINEOPLASTIC AGENTS BOEHRINGER MANNHEIM ITALIA (IT) 1994-11-30 EP disclosed
EP-0471709-A1 RUTHENIUM(III) COMPLEXES AS ANTINEOPLASTIC AGENTS. BOEHRINGER MANNHEIM ITALIA (IT) 1992-02-26 EP disclosed
WO-1990013553-A1 RUTHENIUM(III) COMPLEXES AS ANTINEOPLASTIC AGENTS BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1990-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230065217-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS MRGPRX2, MRGPRX1, MRGPRX4 LTA4H 2941/4885CYP3A4 3553/4885SLC7A5 2686/4885
US-20080152675-A1 Sustained release of drug in an aqueous phase containing at least one amphiphilic polymer; dispersion in a continuous lipid phase; water in oil emulsions; low viscosity for injection; aspartate-glutamate or aspartic-glutamic copolymers; biodrugs PHOSPHO1, GLUL, GRIA1 LTA4H 274/4885CYP3A4 2205/4885SLC7A5 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.