SCHEMBL30799618

SCHEMBL30799618

O=C(c1ccccc1)C1CCc2ccc(Cl)cc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.51
PIN1 Q13526 4/20 0.46
KDM1A O60341 1/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
TAS1R2 Q8TE23 1/20 0.43
MCL1 Q07820 1/20 0.43
MGLL Q99685 2/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
FABP4 P15090 2/20 0.41
ALOX12 P18054 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10467284 0.84 FABP4 (0.49) TRPM8KDM1AMAOAMAOBFABP4
SCHEMBL30799420 0.82 PIN1 (0.48) PIN1MCL1POLBGAAHSD17B10
SCHEMBL30335806 0.82 PIN1 (0.59) TRPM8PIN1TAS1R3TAS1R1TAS1R2
SCHEMBL27914888 0.81 PIN1 (0.59) PIN1MGLLMEN1KMT2A
SCHEMBL27933389 0.81 PIN1 (0.59) PIN1MGLLMEN1KMT2A
SCHEMBL25642142 0.81 PIN1 (0.59) PIN1MGLLMEN1KMT2A
SCHEMBL28002431 0.80 PIN1 (0.66) TRPM8PIN1MCL1POLBGAA
SCHEMBL14916493 0.80 SIRT1 (0.52) TRPM8KDM1AMAOAMAOB
SCHEMBL30799691 0.78 KDM1A (0.48) PIN1KDM1AMCL1
SCHEMBL19469643 0.76 HTR2B (0.41) TRPM8PIN1KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894141-B Method for synthesizing acyl indene alkane derivative 贺州学院 2023-12-22 CN disclosed