Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 15/20 | 0.50 |
| ▸ | GNPAT | O15228 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30799857 | 0.91 | ENPEP (0.49) | ENPEPGNPATALDH1A1PTPN1 | |
| SCHEMBL31181245 | 0.85 | ENPEP (0.57) | ENPEPALDH1A1 | |
| SCHEMBL24178400 | 0.84 | ALDH1A1 (0.59) | ENPEPALDH1A1L3MBTL1 | |
| SCHEMBL30799377 | 0.84 | ENPEP (0.43) | ENPEPGNPATALDH1A1PTPN1L3MBTL1 | |
| SCHEMBL30930149 | 0.84 | ENPEP (0.50) | ENPEPALDH1A1L3MBTL1 | |
| SCHEMBL31181264 | 0.84 | ENPEP (0.56) | ENPEPALDH1A1 | |
| SCHEMBL31091379 | 0.84 | ENPEP (0.56) | ENPEPALDH1A1 | |
| SCHEMBL31181277 | 0.82 | ENPEP (0.55) | ENPEPALDH1A1 | |
| SCHEMBL15692297 | 0.82 | ALDH1A1 (0.58) | ENPEPALDH1A1L3MBTL1 | |
| SCHEMBL20231491 | 0.81 | GNPAT (0.50) | ENPEPGNPATALDH1A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | ENPEP 41/4885GNPAT 3689/4885ALDH1A1 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.