Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15487283 | 1.00 | PDGFRB (0.47) | PDGFRBPDGFRAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL30800021 | 0.94 | KMT2A (0.55) | PDGFRBPDGFRAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL3997475 | 0.80 | RAB9A (0.45) | KMT2AHTTSMN1; SMN2TDP1HPGD | |
| SCHEMBL30799511 | 0.80 | RAB9A (0.45) | KMT2AHTTSMN1; SMN2TDP1HPGD | |
| SCHEMBL29743318 | 0.80 | MMP12 (0.47) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL1875326 | 0.79 | MMP12 (0.46) | PDGFRBPDGFRAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL6364795 | 0.79 | KMT2A (0.46) | KMT2AHTTSMN1; SMN2TDP1HPGD | |
| SCHEMBL30138396 | 0.78 | HTR1A (0.48) | PDGFRBPDGFRAKMT2ASMN1; SMN2ELANE | |
| SCHEMBL15092190 | 0.77 | PDGFRB (0.50) | PDGFRBPDGFRAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL4606421 | 0.77 | MMP12 (0.47) | KMT2AHTTPOLBMMP12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512840-B1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | TSENG YUFENG JANE (US) | 2024-03-06 | — | — | EP | claimed |