Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128462 | 1.00 | POLB (0.36) | POLBMAPTTDP1L3MBTL1KDM4E | |
| SCHEMBL29128406 | 0.85 | DAO (0.39) | POLBMAPTTDP1L3MBTL1KDM4E | |
| SCHEMBL30800064 | 0.85 | DAO (0.39) | POLBMAPTTDP1L3MBTL1KDM4E | |
| SCHEMBL29128494 | 0.83 | MTNR1B (0.31) | — | |
| SCHEMBL30799855 | 0.83 | MTNR1B (0.31) | — | |
| SCHEMBL29128227 | 0.80 | DRD2 (0.33) | MAPTTDP1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL30800013 | 0.80 | ALDH1A1 (0.47) | POLBTDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29128442 | 0.80 | ALDH1A1 (0.47) | POLBTDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL30788470 | 0.76 | ALDH1A1 (0.54) | POLBMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL30799897 | 0.75 | KDM4E (0.33) | KDM4ESMN1; SMN2ALDH1A1LMNAGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |