SCHEMBL30800593

SCHEMBL30800593

O=Cc1ccc(-c2c3ccccc3cc3ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.50
ALDH1A1 P00352 3/20 0.43
CYP2A6 P11509 1/20 0.43
KIF11 P52732 2/20 0.41
CES1 P23141 1/20 0.40
RAB9A P51151 2/20 0.39
BRD4 O60885 1/20 0.39
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
HPGD P15428 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP1A2 P05177 1/20 0.38
GLA P06280 1/20 0.38
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.38
DRD1 P21728 3/20 0.38
GPR84 Q9NQS5 1/20 0.37
CYP3A4 P08684 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4821274 1.00 ALOX5 (0.50) ALOX5ALDH1A1CYP2A6KIF11CES1
SCHEMBL22367087 0.86 ALDH1A1 (0.44) ALDH1A1CYP2A6KIF11RAB9ABRD4
SCHEMBL12571883 0.86 ALOX5 (0.49) ALOX5ALDH1A1CYP2A6KIF11CES1
SCHEMBL4547729 0.86 ALDH1A1 (0.52) ALDH1A1CYP2A6KIF11BRD4KDM4E
SCHEMBL30825159 0.84 ALOX5 (0.38) ALOX5ALDH1A1CYP2A6KIF11RAB9A
SCHEMBL16381821 0.82 ALDH1A1 (0.54) ALDH1A1CYP2A6KIF11BRD4KDM4E
SCHEMBL30825196 0.82 ALOX5 (0.36) ALOX5ALDH1A1CYP2A6MEN1HPGD
SCHEMBL12571878 0.81 ALOX5 (0.47) ALOX5ALDH1A1CYP2A6KIF11CES1
SCHEMBL30524232 0.81 ALOX5 (0.47) ALOX5ALDH1A1CYP2A6KIF11CES1
SCHEMBL669208 0.81 ALOX5 (0.50) ALOX5ALDH1A1CES1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603224-A Anthracene-based photochromic compound containing sulfur-containing hetero spiro unit, and preparation method and application thereof 东南大学 2024-02-27 CN disclosed