Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 12/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hispitolide D SCHEMBL29711300 | 0.85 | PAX8 (0.59) | PAX8PTGS2PKMNLRP3 | |
| Hispitolide C SCHEMBL29711430 | 0.85 | PAX8 (0.59) | PAX8PTGS2PKMNLRP3 | |
| Coronopilin SCHEMBL8422737 | 0.77 | PAX8 (1.00) | PAX8PTGS2PKMNLRP3 | |
| SCHEMBL4067886 | 0.61 | PAX8 (0.59) | PAX8PTGS2PKMNLRP3 | |
| SCHEMBL4060418 | 0.61 | PAX8 (0.52) | PAX8PTGS2PKMNLRP3 | |
| Parthenin SCHEMBL382003 | 0.60 | PAX8 (0.58) | PAX8PTGS2PKMNLRP3 | |
| Hymenin SCHEMBL11892893 | 0.60 | PAX8 (0.58) | PAX8PTGS2PKMNLRP3 | |
| Hymenin SCHEMBL12355327 | 0.60 | PAX8 (0.58) | PAX8PTGS2PKMNLRP3 | |
| SCHEMBL4067330 | 0.60 | PAX8 (0.61) | PAX8PTGS2PKMNLRP3 | |
| Hymenin SCHEMBL29711376 | 0.60 | PAX8 (0.58) | PAX8PTGS2PKMNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586258-A | Covalent evodiamine derivative with antitumor activity and application thereof | 中国人民解放军海军军医大学 | 2024-02-23 | — | — | CN | disclosed |