Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27119074 | 1.00 | MRGPRX4 (0.37) | MRGPRX4CYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL22451971 | 0.86 | MRGPRX4 (0.49) | MRGPRX4CYP1A2ALDH1A1 | |
| SCHEMBL26966747 | 0.84 | PTGER1 (0.40) | PDE5A | |
| SCHEMBL23567539 | 0.84 | NR1D1 (0.40) | MRGPRX4CYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL15865618 | 0.80 | CYP1A2 (0.36) | MRGPRX4CYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL15865612 | 0.80 | CYP1A2 (0.36) | MRGPRX4CYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL27152458 | 0.80 | PPARG (0.39) | PDE5A | |
| SCHEMBL2352200 | 0.78 | CYP1A2 (0.44) | MRGPRX4CYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL29844105 | 0.78 | CYP1A2 (0.44) | MRGPRX4CYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL27119075 | 0.78 | SUCNR1 (0.46) | NQO2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044554-A1 | VHH ANTIBODY CONJUGATES WITH HETEROARYL CHELATORS | Abdera Therapeutics Inc. (US) | 2024-02-29 | — | — | WO | disclosed |