Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22451837 | 0.92 | MRGPRX4 (0.49) | MRGPRX4MAPTCYP1A2GAARECQL | |
| SCHEMBL30801055 | 0.86 | MRGPRX4 (0.37) | MRGPRX4CYP1A2ALDH1A1 | |
| SCHEMBL27119074 | 0.86 | MRGPRX4 (0.37) | MRGPRX4CYP1A2ALDH1A1 | |
| SCHEMBL22451974 | 0.83 | FAAH (0.45) | MRGPRX4HPGDL3MBTL1 | |
| SCHEMBL22451836 | 0.82 | BRD4 (0.49) | MRGPRX4MAPTCYP1A2GAARECQL | |
| SCHEMBL29683735 | 0.82 | BRD4 (0.49) | MRGPRX4MAPTCYP1A2GAARECQL | |
| SCHEMBL24440581 | 0.81 | MRGPRX4 (0.45) | MRGPRX4MAPTCYP1A2GAARECQL | |
| SCHEMBL31721222 | 0.80 | MRGPRX4 (0.49) | MRGPRX4MAPTCYP1A2GAARECQL | |
| SCHEMBL15865609 | 0.77 | BRD4 (0.47) | MRGPRX4MAPTPARP1SMN1; SMN2KDM4E | |
| SCHEMBL12454120 | 0.76 | BRD4 (0.46) | MRGPRX4MAPTPARP1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220160908-A1 | CHELATORS AND METHODS OF MAKING AND USING SAME | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2022-05-26 | — | — | US | disclosed |
| US-20220160908-A1 | CHELATORS AND METHODS OF MAKING AND USING SAME | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2022-05-26 | — | — | US | disclosed |
| WO-2020186328-A1 | CHELATORS AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2020-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160908-A1 | CHELATORS AND METHODS OF MAKING AND USING SAME | TFRC, SLC40A1, FOLH1 | MRGPRX4 1100/4885MAPT 4292/4885CYP1A2 4245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.