Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30801352

NNC(=O)c1cc[n+](Cc2cn(-c3ccccc3)nn2)cc1.O=C(O)C(F)(F)F.O=C([O-])C(F)(F)F

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.45
NOTUM Q6P988 3/20 0.40
MAOA P21397 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
NPC1 O15118 1/20 0.40
POLB P06746 3/20 0.38
MAOB P27338 2/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
DDX3X O00571 1/20 0.38
APP P05067 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
GLA P06280 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL30801355 0.90 MIF (0.43) MIFNOTUMMAOAL3MBTL1NPC1
Trifluoroacetic Acid SCHEMBL23326692 0.85 L3MBTL1 (0.47) MIFNOTUML3MBTL1NPC1POLB
Trifluoroacetic Acid SCHEMBL23326865 0.77 L3MBTL1 (0.43) MIFNOTUML3MBTL1NPC1POLB
SCHEMBL30801359 0.76 L3MBTL1 (0.55) MIFNOTUMMAOAL3MBTL1NPC1
SCHEMBL23326705 0.71 MAOA (0.43) MIFNOTUMMAOAL3MBTL1NPC1
Formic Acid SCHEMBL30801353 0.69 NOTUM (0.38) MIFNOTUMMAOAL3MBTL1NPC1
Formic Acid SCHEMBL30801354 0.69 NOTUM (0.38) MIFNOTUMMAOAL3MBTL1NPC1
Benzoic Acid Hydrazide SCHEMBL5591378 0.67 CES1 (0.52) L3MBTL1NPC1ALDH1A1GAAMAPT
SCHEMBL23326579 0.63 GLA (0.46) MIFNOTUMMAOAL3MBTL1NPC1
SCHEMBL15057639 0.63 NOTUM (0.63) MIFNOTUMMAOAL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11885818-B2 Reagent for mass spectrometry ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2024-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11885818-B2 Reagent for mass spectrometry SRMS, PTMS, MMAB MIF 1934/4885NOTUM 212/4885MAOA 854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.