Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528570 | 0.87 | ALDH1A1 (0.37) | LMNACYP2D6SPHK1TP53PLA2G1B | |
| SCHEMBL7189754 | 0.87 | OPRM1 (0.48) | LMNACYP2D6SPHK1TP53PLA2G1B | |
| SCHEMBL10705706 | 0.84 | LMNA (0.48) | LMNACYP2D6SPHK1TP53PLA2G1B | |
| Fluoride SCHEMBL30636245 | 0.83 | LMNA (0.43) | LMNACYP2D6SPHK1TP53PLA2G1B | |
| SCHEMBL322499 | 0.81 | LMNA (0.47) | LMNACYP2D6SPHK1TP53PLA2G1B | |
| SCHEMBL9766793 | 0.81 | PLA2G1B (0.50) | LMNACYP2D6SPHK1TP53PLA2G1B | |
| SCHEMBL9244931 | 0.81 | PLA2G1B (0.50) | LMNACYP2D6SPHK1TP53PLA2G1B | |
| SCHEMBL6908178 | 0.81 | PLA2G1B (0.50) | LMNACYP2D6SPHK1TP53PLA2G1B | |
| SCHEMBL15477624 | 0.81 | PLA2G1B (0.50) | LMNACYP2D6SPHK1TP53PLA2G1B | |
| SCHEMBL7187154 | 0.80 | PLA2G1B (0.39) | SPHK1TP53PLA2G1BPLA2G2ALAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618938-A1 | NOVEL DENTIFRICE COMPOSITIONS AND USES | Haleon UK IP Limited (GB) | 2025-09-24 | — | — | EP | disclosed |
| US-20250281375-A1 | NON-AQUEOUS DENTIFRICE COMPOSITION | Haleon UK IP Limited (GB) | 2025-09-11 | — | — | US | disclosed |
| EP-4577311-A1 | TOOTHPASTE TABLET COMPOSITION | Haleon UK IP Limited (GB) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024041876-A1 | TOOTHPASTE TABLET COMPOSITION | Haleon UK IP Limited (GB) | 2024-02-29 | — | — | WO | disclosed |