Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19853751 | 0.88 | FKBP1A (0.37) | ALDH1A1GAANPC1MAPK1RAB9A | |
| SCHEMBL22863046 | 0.83 | GAA (0.36) | ALDH1A1HTR2CGAANPC1MAPK1 | |
| SCHEMBL19627475 | 0.82 | ALDH1A1 (0.36) | ALDH1A1GAANPC1MAPK1RAB9A | |
| SCHEMBL19627463 | 0.82 | ALDH1A1 (0.36) | ALDH1A1GAANPC1MAPK1RAB9A | |
| SCHEMBL17712401 | 0.82 | ALDH1A1 (0.36) | ALDH1A1GAANPC1MAPK1RAB9A | |
| SCHEMBL21034903 | 0.82 | CYP3A4 (0.37) | ALDH1A1HTR2CGAANPC1RAB9A | |
| SCHEMBL19853752 | 0.80 | CSNK1A1 (0.40) | ALDH1A1GAAMAPK1SMN1; SMN2CYP3A4 | |
| SCHEMBL19839375 | 0.79 | SLC1A3 (0.39) | ALDH1A1CYP2D6MMP2MMP9ADAM17 | |
| SCHEMBL19839377 | 0.79 | SLC1A3 (0.39) | ALDH1A1CYP2D6MMP2MMP9ADAM17 | |
| SCHEMBL30801696 | 0.78 | USP30 (0.41) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |