Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | OTUD7B | Q6GQQ9 | 3/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801790 | 1.00 | USP30 (0.43) | USP30CYP3A4CYP1A2CYP2C9CASP1 | |
| SCHEMBL30801777 | 0.85 | HTR2C (0.38) | CYP3A4CYP1A2CYP2C9TP53BACE1 | |
| SCHEMBL30801874 | 0.85 | HTR2C (0.38) | CYP3A4CYP1A2CYP2C9TP53BACE1 | |
| SCHEMBL23574148 | 0.84 | USP30 (0.52) | USP30CYP3A4CYP1A2CYP2C9CASP1 | |
| SCHEMBL23573999 | 0.84 | USP30 (0.52) | USP30CYP3A4CYP1A2CYP2C9CASP1 | |
| SCHEMBL23574000 | 0.84 | USP30 (0.52) | USP30CYP3A4CYP1A2CYP2C9CASP1 | |
| SCHEMBL30801732 | 0.82 | USP30 (0.42) | USP30CYP3A4CYP1A2CYP2C9CASP1 | |
| SCHEMBL30801856 | 0.82 | USP30 (0.42) | USP30CYP3A4CYP1A2CYP2C9CASP1 | |
| SCHEMBL30801797 | 0.81 | GRM5 (0.47) | USP30CYP3A4CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL30801780 | 0.80 | GRM5 (0.41) | USP30DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |