Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23573995 | 0.85 | USP30 (0.47) | GRM5DRD2DRD3USP30ALOX5 | |
| SCHEMBL23573993 | 0.85 | USP30 (0.47) | GRM5DRD2DRD3USP30ALOX5 | |
| SCHEMBL30801717 | 0.80 | NOTUM (0.46) | GRM5DRD2DRD3USP30ALOX5 | |
| SCHEMBL30801818 | 0.80 | GRM5 (0.43) | GRM5DRD2DRD3USP30ALOX5 | |
| SCHEMBL30801795 | 0.80 | USP30 (0.43) | DRD2DRD3USP30 | |
| SCHEMBL30801790 | 0.80 | USP30 (0.43) | DRD2DRD3USP30 | |
| Hydrochloric Acid SCHEMBL3608093 | 0.77 | DRD2 (0.50) | DRD2DRD3ALOX5NOTUMNSD2 | |
| SCHEMBL30801797 | 0.74 | GRM5 (0.47) | GRM5USP30 | |
| SCHEMBL30801856 | 0.73 | USP30 (0.42) | DRD2DRD3USP30 | |
| SCHEMBL30801732 | 0.73 | USP30 (0.42) | DRD2DRD3USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |