Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801868 | 0.89 | DPP4 (0.42) | DPP4KMOHTR2CSMN1; SMN2USP30 | |
| SCHEMBL30801797 | 0.81 | GRM5 (0.47) | DPP4USP30ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL23574136 | 0.79 | USP30 (0.46) | DPP4KMONPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23574139 | 0.79 | USP30 (0.46) | DPP4KMONPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30801870 | 0.79 | GRM5 (0.48) | DPP4USP30CYP1A2 | |
| SCHEMBL30801719 | 0.79 | DRD2 (0.37) | HTR2CNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL30801763 | 0.77 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2TSHRLMNA | |
| SCHEMBL30801761 | 0.73 | COMT (0.38) | HTR2CUSP30 | |
| SCHEMBL30801833 | 0.71 | F10 (0.40) | HTR2C | |
| SCHEMBL30801844 | 0.71 | DRD2 (0.49) | HTR2CSMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |