Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801761 | 0.80 | COMT (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL30801864 | 0.79 | ALDH1A1 (0.51) | CYP17A1HTR2AHTR2CHTR2B | |
| SCHEMBL30801853 | 0.79 | ALDH1A1 (0.41) | CYP17A1HTR2AHTR2CHTR2B | |
| SCHEMBL23574153 | 0.78 | USP30 (0.45) | ADRB1CYP17A1TRPV1 | |
| SCHEMBL23574150 | 0.78 | USP30 (0.45) | ADRB1CYP17A1TRPV1 | |
| SCHEMBL30801886 | 0.78 | USP30 (0.45) | ADRB1CYP17A1TRPV1 | |
| SCHEMBL30801785 | 0.77 | GRIN1 (0.38) | HTR2C | |
| SCHEMBL30801796 | 0.76 | USP30 (0.36) | HTR2CHTR2B | |
| SCHEMBL3081103 | 0.74 | ADRB1 (0.62) | ADRB1CYP17A1HTR2CADRB2NCF1 | |
| SCHEMBL21858471 | 0.73 | ADRB1 (0.60) | ADRB1CYP17A1ADRB2NCF1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |