Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801845 | 0.87 | HTR2A (0.39) | HTR2CHTR2AHTR2BDRD2DRD3 | |
| SCHEMBL30801770 | 0.85 | TAAR1 (0.37) | ALDH1A1HTR2CHTR2AHTR2B | |
| SCHEMBL30801864 | 0.85 | ALDH1A1 (0.51) | ALDH1A1HTR2CGLAHTR3EHTR3B | |
| SCHEMBL30801818 | 0.85 | GRM5 (0.43) | HTR2CHTR2BDRD2DRD3 | |
| SCHEMBL23573926 | 0.82 | USP30 (0.46) | ALDH1A1GLATSHRHTTHTR7 | |
| SCHEMBL30986846 | 0.82 | USP30 (0.46) | ALDH1A1GLATSHRHTTHTR7 | |
| SCHEMBL23573929 | 0.82 | USP30 (0.46) | ALDH1A1GLATSHRHTTHTR7 | |
| SCHEMBL30801872 | 0.79 | ADRB1 (0.53) | HTR2CHTR2AHTR2BCYP17A1 | |
| Hydrochloric Acid SCHEMBL3606971 | 0.78 | MAPT (0.52) | ALDH1A1HTR2CGLAHTR3EHTR3B | |
| SCHEMBL30801785 | 0.76 | GRIN1 (0.38) | ALDH1A1HTR2CGLAHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |