Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 7/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 2/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801729 | 1.00 | HTR1A (0.34) | HTR1ASLC6A2SLC6A4SLC6A3BRD4 | |
| SCHEMBL23113619 | 0.83 | USP30 (0.44) | BRD4OTUD7BUSP30 | |
| SCHEMBL23113620 | 0.83 | USP30 (0.44) | BRD4OTUD7BUSP30 | |
| SCHEMBL23113645 | 0.83 | USP30 (0.44) | BRD4OTUD7BUSP30 | |
| SCHEMBL30801756 | 0.77 | SLC6A2 (0.34) | HTR1ASLC6A2SLC6A4SLC6A3BRD4 | |
| SCHEMBL30801808 | 0.77 | HTR2C (0.35) | HTR1ASLC6A2SLC6A4SLC6A3BRD4 | |
| SCHEMBL30801768 | 0.77 | HTR2C (0.35) | HTR1ASLC6A2SLC6A4SLC6A3BRD4 | |
| SCHEMBL30801822 | 0.74 | LTA4H (0.49) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL30801891 | 0.70 | NPC1 (0.37) | SLC6A2TAAR1 | |
| SCHEMBL30801761 | 0.68 | COMT (0.38) | HTR1AHTR2CHTR2BHTR2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |