Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 6/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3612152 | 0.80 | LTA4H (0.40) | LTA4HMGLLTAAR1HTR2AHTR2C | |
| SCHEMBL30801775 | 0.78 | HTR1A (0.49) | ALDH1A1MGLLTAAR1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL3609734 | 0.76 | TAAR1 (0.42) | ALDH1A1TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL23574011 | 0.76 | USP30 (0.45) | ALDH1A1GAAMGLLPLCG1 | |
| SCHEMBL23574013 | 0.76 | USP30 (0.45) | ALDH1A1GAAMGLLPLCG1 | |
| SCHEMBL30801829 | 0.74 | SLC6A2 (0.51) | ALDH1A1LMNAHTR2AHTR2CHTR2B | |
| SCHEMBL30801844 | 0.74 | DRD2 (0.49) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL30801884 | 0.74 | HTR1A (0.34) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL1514961 | 0.73 | HTR3E (0.44) | ALDH1A1MGLLTAAR1HTR2AHTR2C | |
| SCHEMBL1514885 | 0.73 | HTR3E (0.44) | ALDH1A1MGLLTAAR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |