(-)-Asimilobine

(-)-Asimilobine

SCHEMBL30801946

COc1c(O)cc2c3c1-c1ccccc1C[C@H]3NCC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 6/20 1.00
DRD2 P14416 6/20 1.00
DRD1 P21728 5/20 1.00
PTPRCAP Q14761 2/20 0.77
HTR2A P28223 2/20 0.69
HTR2B P41595 1/20 0.69
DYRK1A Q13627 1/20 0.61
KDM4E B2RXH2 1/20 0.61
ALDH1A1 P00352 1/20 0.61
HPGD P15428 1/20 0.61
HSD17B10 Q99714 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asimilobine SCHEMBL29787879 1.00 HTR2C (1.00) HTR2CDRD2DRD1PTPRCAPHTR2A
Nornuciferine SCHEMBL29787894 0.87 HTR2C (1.00) HTR2CDRD2DRD1PTPRCAPHTR2A
Nornuciferine SCHEMBL29501026 0.87 HTR2C (1.00) HTR2CDRD2DRD1PTPRCAPHTR2A
Hydrochloric Acid SCHEMBL29933623 0.85 HTR2C (0.74) HTR2CDRD2DRD1PTPRCAPHTR2A
Hydrochloric Acid SCHEMBL29933899 0.84 HTR2C (0.72) HTR2CDRD2DRD1PTPRCAPHTR2A
SCHEMBL29506718 0.83 HTR2C (0.77) HTR2CDRD2DRD1PTPRCAPHTR2A
SCHEMBL14259791 0.83 DRD1 (0.71) HTR2CDRD2DRD1PTPRCAPHTR2B
Norboldine SCHEMBL29886755 0.83 DRD1 (0.71) HTR2CDRD2DRD1PTPRCAPHTR2B
Norboldine SCHEMBL14367906 0.83 DRD1 (0.71) HTR2CDRD2DRD1PTPRCAPHTR2B
Norboldine SCHEMBL29402012 0.83 DRD1 (0.71) HTR2CDRD2DRD1PTPRCAPHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119700765-A Di-Caulophyllum dopamine D2 receptor agonist, application thereof and pharmaceutical composition 中国科学院大连化学物理研究所 2025-03-28 CN disclosed
US-20240100113-A1 TERPENE-CONTAINING COMPOSITIONS QSI HOLDING COMPANY INC (US) 2024-03-28 US disclosed