Nornuciferine

Nornuciferine

SCHEMBL29787894

COc1cc2c3c(c1OC)-c1ccccc1CC3NCC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 7/20 1.00
DRD1 P21728 5/20 1.00
PTPRCAP Q14761 1/20 1.00
DRD2 P14416 5/20 0.77
KDM4E B2RXH2 1/20 0.72
ALDH1A1 P00352 1/20 0.72
HPGD P15428 1/20 0.72
HSD17B10 Q99714 1/20 0.72
DYRK1A Q13627 1/20 0.67
HTR7 P34969 2/20 0.61
HTR2A P28223 2/20 0.61
PNPLA2 Q96AD5 1/20 0.61
ADRB2 P07550 3/20 0.60
HTR2B P41595 2/20 0.60
ADRB1 P08588 1/20 0.60
HTR1A P08908 1/20 0.60
ADRA2A P08913 1/20 0.60
ADRB3 P13945 1/20 0.60
ADRA2B P18089 1/20 0.60
HTR1D P28221 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nornuciferine SCHEMBL29501026 1.00 HTR2C (1.00) HTR2CDRD1PTPRCAPDRD2KDM4E
SCHEMBL30029891 0.87 HTR2C (0.77) HTR2CDRD1PTPRCAPDRD2KDM4E
SCHEMBL29506718 0.87 HTR2C (0.77) HTR2CDRD1PTPRCAPDRD2KDM4E
(-)-Asimilobine SCHEMBL30801946 0.87 HTR2C (1.00) HTR2CDRD1PTPRCAPDRD2KDM4E
Asimilobine SCHEMBL29787879 0.87 HTR2C (1.00) HTR2CDRD1PTPRCAPDRD2KDM4E
SCHEMBL9976807 0.86 DRD1 (0.76) HTR2CDRD1PTPRCAPDRD2KDM4E
SCHEMBL23949488 0.85 DRD2 (1.00) HTR2CDRD1PTPRCAPDRD2KDM4E
SCHEMBL563496 0.85 DRD2 (1.00) HTR2CDRD1PTPRCAPDRD2KDM4E
Laurotetanine SCHEMBL905065 0.81 DRD2 (0.74) HTR2CDRD1PTPRCAPDRD2KDM4E
Laurotetanine SCHEMBL31300083 0.81 DRD2 (0.74) HTR2CDRD1PTPRCAPDRD2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119656653-B Application of cyanamide waste residue carbon in lotus alkaloid extraction, solid phase extraction adsorbent and application thereof 浙江工业大学 2025-06-13 CN claimed
CN-120053346-A Lotus seedpod or lotus seed shell extract and preparation method and application thereof 湖南科技大学 2025-05-30 CN claimed
CN-119656653-A Application of cyanamide waste residue carbon in lotus alkaloid extraction, solid phase extraction adsorbent and application thereof 浙江工业大学 2025-03-21 CN claimed
CN-118091005-A Method for detecting multiple components in deer astragalus kidney-tonifying particles 上海市第七人民医院(上海中医药大学附属第七人民医院) 2024-05-28 CN claimed
CN-117982560-A Lotus leaf extract and preparation method and application thereof 清华大学 2024-05-07 CN claimed
CN-120053346-A Lotus seedpod or lotus seed shell extract and preparation method and application thereof 湖南科技大学 2025-05-30 CN disclosed
CN-117982560-A Lotus leaf extract and preparation method and application thereof 清华大学 2024-05-07 CN disclosed
CN-116818927-A System and method for detecting and monitoring N-nornuciferine content in different lotus 北京电子科技职业学院 2023-09-29 CN disclosed
CN-115896058-B O-methyltransferase protein with high specific catalytic function on various BIAS parent nuclei, and encoding gene and application thereof 中国中医科学院中药研究所 2023-07-14 CN disclosed
CN-115896058-A O-methyltransferase protein with high specific catalytic function on multiple BIAS mother nuclei and coding gene and application thereof 中国中医科学院中药研究所 2023-04-04 CN disclosed
CN-109689026-B Method for increasing lipolysis using a composition comprising a bioactive lotus extract ISP投资有限公司 2022-08-30 CN disclosed
CN-114891840-A Lotus leaf O-methyltransferase and application of encoding gene thereof in synthesis of benzylisoquinoline alkaloid and phenylpropanoic acid compounds 中国中医科学院中药研究所 2022-08-12 CN disclosed