Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 5/20 | 0.71 |
| ▸ | DRD2 | P14416 | 4/20 | 0.71 |
| ▸ | HTR2C | P28335 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norboldine SCHEMBL14367906 | 1.00 | DRD1 (0.71) | DRD1DRD2HTR2CALDH1A1HPGD | |
| Norboldine SCHEMBL27987614 | 1.00 | DRD1 (0.71) | DRD1DRD2HTR2CALDH1A1HPGD | |
| Norboldine SCHEMBL29886755 | 1.00 | DRD1 (0.71) | DRD1DRD2HTR2CALDH1A1HPGD | |
| SCHEMBL30828734 | 0.96 | DRD1 (0.70) | DRD1DRD2HTR2CALDH1A1HPGD | |
| SCHEMBL14259791 | 0.95 | DRD1 (0.71) | DRD1DRD2HTR2CALDH1A1HPGD | |
| Laurotetanine SCHEMBL905065 | 0.94 | DRD2 (0.74) | DRD1DRD2HTR2CALDH1A1HPGD | |
| Laurotetanine SCHEMBL31300083 | 0.94 | DRD2 (0.74) | DRD1DRD2HTR2CALDH1A1HPGD | |
| Laurotetanine SCHEMBL905125 | 0.94 | DRD2 (0.74) | DRD1DRD2HTR2CALDH1A1HPGD | |
| SCHEMBL14259787 | 0.92 | ALDH1A1 (0.65) | DRD1DRD2HTR2CALDH1A1HPGD | |
| SCHEMBL11055620 | 0.88 | ALDH1A1 (0.69) | DRD1DRD2HTR2CALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114377013-B | Application of norboldine and method for promoting differentiation of mesenchymal stem cells into osteoblasts | 遵义医科大学附属医院 | 2023-12-19 | — | — | CN | claimed |
| CN-114377013-A | Application of norboldine and method for promoting mesenchymal stem cells to differentiate into osteoblasts | 遵义医科大学附属医院 | 2022-04-22 | — | — | CN | claimed |
| CN-118924753-A | Medicine and application thereof in preparation of medicine for preventing or treating osteoporosis | 遵义医科大学附属医院 | 2024-11-12 | — | — | CN | disclosed |
| CN-117723684-A | Cordate houttuynia quality analysis method based on metabonomics | 中山市中智药业集团有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114377013-B | Application of norboldine and method for promoting differentiation of mesenchymal stem cells into osteoblasts | 遵义医科大学附属医院 | 2023-12-19 | — | — | CN | disclosed |
| CN-114377013-B | Application of norboldine and method for promoting differentiation of mesenchymal stem cells into osteoblasts | 遵义医科大学附属医院 | 2023-12-19 | — | — | CN | disclosed |
| CN-116570628-A | Clostridium northwest for treating solid tumors in humans | 生物医学谷探索股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-108911982-B | Environment-friendly method for synthesizing acyloxy-substituted styrene compound | 徐州博康信息化学品有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114377013-A | Application of norboldine and method for promoting mesenchymal stem cells to differentiate into osteoblasts | 遵义医科大学附属医院 | 2022-04-22 | — | — | CN | disclosed |
| CN-114377013-A | Application of norboldine and method for promoting mesenchymal stem cells to differentiate into osteoblasts | 遵义医科大学附属医院 | 2022-04-22 | — | — | CN | disclosed |
| CN-114377013-A | Application of norboldine and method for promoting mesenchymal stem cells to differentiate into osteoblasts | 遵义医科大学附属医院 | 2022-04-22 | — | — | CN | disclosed |
| CN-113197934-B | Lindera aggregata leaf extract and preparation method and application thereof | 浙大宁波理工学院 | 2022-03-11 | — | — | CN | disclosed |