Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.77 |
| ▸ | DRD1 | P21728 | 3/20 | 0.77 |
| ▸ | PTPRCAP | Q14761 | 2/20 | 0.77 |
| ▸ | DRD2 | P14416 | 3/20 | 0.71 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30029891 | 1.00 | HTR2C (0.77) | HTR2CDRD1PTPRCAPDRD2HTR2B | |
| SCHEMBL29039792 | 0.87 | DRD2 (0.81) | HTR2CDRD1PTPRCAPDRD2HTR2A | |
| Nornuciferine SCHEMBL29501026 | 0.87 | HTR2C (1.00) | HTR2CDRD1PTPRCAPDRD2HTR2B | |
| Nornuciferine SCHEMBL29787894 | 0.87 | HTR2C (1.00) | HTR2CDRD1PTPRCAPDRD2HTR2B | |
| SCHEMBL9976810 | 0.86 | DRD2 (0.63) | HTR2CDRD1PTPRCAPDRD2HTR2A | |
| SCHEMBL11055620 | 0.83 | ALDH1A1 (0.69) | HTR2CDRD1PTPRCAPDRD2HTR2B | |
| Asimilobine SCHEMBL29787879 | 0.83 | HTR2C (1.00) | HTR2CDRD1PTPRCAPDRD2HTR2B | |
| (-)-Asimilobine SCHEMBL30801946 | 0.83 | HTR2C (1.00) | HTR2CDRD1PTPRCAPDRD2HTR2B | |
| SCHEMBL29398835 | 0.83 | ALDH1A1 (0.69) | HTR2CDRD1PTPRCAPDRD2HTR2B | |
| SCHEMBL27850407 | 0.83 | ALDH1A1 (0.69) | HTR2CDRD1PTPRCAPDRD2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416221-B | Total synthesis method of natural product phenanthrene alkaloid glycoside compound H4 | 江西中医药大学 | 2022-03-11 | — | — | CN | disclosed |