Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25277595 | 1.00 | ITGB3 (0.51) | ITGB3ITGA2BACEPTPN1CTSS | |
| SCHEMBL30802009 | 0.88 | KLK5 (0.44) | ITGB3ITGA2BACEPTPN1CTSS | |
| SCHEMBL25268638 | 0.88 | KLK5 (0.44) | ITGB3ITGA2BACEPTPN1CTSS | |
| SCHEMBL18681306 | 0.84 | CA1 (0.40) | ITGB3ITGA2BCTSSCTSKCTSL | |
| SCHEMBL16487110 | 0.82 | ATM (0.41) | ITGB3ITGA2BCTSSCTSKHDAC8 | |
| SCHEMBL30801968 | 0.81 | CTSK (0.38) | ITGB3ITGA2BACEPTPN1CTSS | |
| SCHEMBL28583142 | 0.80 | ACE (0.54) | ITGB3ITGA2BACEPTPN1CTSS | |
| SCHEMBL29039971 | 0.80 | ACE (0.54) | ITGB3ITGA2BACEPTPN1CTSS | |
| SCHEMBL23295688 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BACEPTPN1CTSS | |
| SCHEMBL23295686 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BACEPTPN1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054603-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |