Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668749 | 0.82 | KIF11 (0.37) | CYP2A6ALDH1A1POLBNOS3NOS1 | |
| SCHEMBL6909657 | 0.80 | CYP2A6 (0.43) | CYP2A6ALDH1A1POLBNOS3NOS1 | |
| SCHEMBL9667455 | 0.75 | MAOA (0.41) | PGRTSHR | |
| SCHEMBL2326687 | 0.74 | KCNH2 (0.42) | CYP2A6ALDH1A1POLBCA12CA2 | |
| SCHEMBL3092427 | 0.74 | POLB (0.42) | CYP2A6ALDH1A1POLBNOS3NOS1 | |
| SCHEMBL18288022 | 0.73 | ALDH1A1 (0.42) | ALDH1A1NOS1TSHR | |
| SCHEMBL18721985 | 0.73 | POLB (0.38) | CYP2A6ALDH1A1POLBNOS3NOS1 | |
| SCHEMBL2673169 | 0.72 | CYP2A6 (0.39) | CYP2A6ALDH1A1 | |
| SCHEMBL703760 | 0.71 | CYP2A6 (0.46) | CYP2A6ALDH1A1POLBCA12CA2 | |
| SCHEMBL9523186 | 0.71 | HRH3 (0.32) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| WO-2012025182-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |