Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CKS1B | P61024 | 1/20 | 0.30 |
| ▸ | SKP1 | P63208 | 1/20 | 0.30 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29845582 | 0.87 | SSTR4 (0.37) | PAX8SSTR4NPSR1 | |
| SCHEMBL23107325 | 0.87 | SSTR4 (0.37) | PAX8SSTR4NPSR1 | |
| SCHEMBL29235733 | 0.86 | NOTUM (0.36) | PAX8SSTR4TTKAAK1NPSR1 | |
| SCHEMBL30801976 | 0.84 | PAX8 (0.34) | PAX8SSTR4TTKAAK1 | |
| SCHEMBL29598178 | 0.83 | TARBP2 (0.38) | PAX8SSTR4NPSR1 | |
| SCHEMBL29859711 | 0.83 | TARBP2 (0.38) | PAX8SSTR4NPSR1 | |
| SCHEMBL30075039 | 0.82 | SSTR4 (0.39) | PAX8SSTR4TTKBRD4CKS1B | |
| SCHEMBL21566105 | 0.82 | SSTR4 (0.39) | PAX8SSTR4TTKBRD4CKS1B | |
| SCHEMBL30802023 | 0.81 | LMNA (0.37) | PAX8NPSR1 | |
| SCHEMBL31709475 | 0.78 | PAX8 (0.36) | PAX8SSTR4TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054603-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |