Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31709536 | 0.88 | SSTR4 (0.36) | SSTR4ACACBCTSSCTSKPLCG1 | |
| SCHEMBL13291287 | 0.85 | PAX8 (0.36) | PAX8CTSSUSP30TTKPLCG1 | |
| SCHEMBL21566105 | 0.80 | SSTR4 (0.39) | PAX8SSTR4TTKNCEH1 | |
| SCHEMBL30075039 | 0.80 | SSTR4 (0.39) | PAX8SSTR4TTKNCEH1 | |
| SCHEMBL30802108 | 0.78 | PAX8 (0.37) | PAX8SSTR4TTK | |
| SCHEMBL29235733 | 0.76 | NOTUM (0.36) | PAX8SSTR4TTKNCEH1 | |
| SCHEMBL13291265 | 0.76 | XDH (0.41) | PAX8CTSS | |
| SCHEMBL2956932 | 0.76 | PAX8 (0.39) | PAX8CTSSCTSKUSP30NCEH1 | |
| SCHEMBL1922821 | 0.75 | PAX8 (0.37) | PAX8SSTR4TTK | |
| SCHEMBL31453184 | 0.75 | PAX8 (0.38) | PAX8SSTR4TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014147-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250340551-A1 | SMALL MOLECULE MODULATORS OF STAT6 | GILEAD SCIENCES INC (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | PAX8 1755/4885SSTR4 741/4885ACACB 2062/4885 |
| US-20250340551-A1 | SMALL MOLECULE MODULATORS OF STAT6 | STAT6, STAT1, STAT5B | PAX8 1772/4885SSTR4 1926/4885ACACB 1463/4885 |
| US-20260014147-A1 | STAT6 DEGRADERS | STAT6, NCOR1, CBR1 | PAX8 2583/4885SSTR4 149/4885ACACB 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.