Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31667435 | 0.82 | MIF (0.53) | TSHRALDH1A1SMN1; SMN2POLBRAB9A | |
| SCHEMBL25337913 | 0.81 | SIGMAR1 (0.45) | TSHRHPGDMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14800038 | 0.81 | MIF (0.44) | TSHRHPGDMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18189848 | 0.81 | NPC1 (0.52) | TSHRHPGDMAPK1ALDH1A1NPSR1 | |
| SCHEMBL29520454 | 0.80 | NPC1 (0.52) | TSHRALDH1A1SMN1; SMN2POLBRAB9A | |
| SCHEMBL30804514 | 0.80 | KMO (0.56) | HPGDALDH1A1NPSR1SMN1; SMN2POLB | |
| SCHEMBL32686737 | 0.79 | NPC1 (0.40) | TSHRHPGDMAPK1ALDH1A1MIF | |
| SCHEMBL32686754 | 0.79 | NPC1 (0.43) | ALDH1A1MIFNPC1 | |
| SCHEMBL29460879 | 0.79 | NPC1 (0.42) | NPC1 | |
| SCHEMBL16475228 | 0.79 | NPC1 (0.42) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583977-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024052512-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-14 | — | — | WO | disclosed |