Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 15/20 | 0.49 |
| ▸ | PREP | P48147 | 13/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.49 |
| ▸ | DPP4 | P27487 | 11/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.46 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29162866 | 1.00 | FAP (0.49) | FAPPREPDPP8DPP9DPP4 | |
| SCHEMBL23876857 | 0.81 | PREP (0.67) | FAPPREPDPP8DPP9DPP4 | |
| SCHEMBL29162847 | 0.81 | PREP (0.67) | FAPPREPDPP8DPP9DPP4 | |
| SCHEMBL29975671 | 0.81 | PREP (0.67) | FAPPREPDPP8DPP9DPP4 | |
| SCHEMBL25890370 | 0.70 | FAP (0.74) | FAPPREPDPP8DPP9DPP4 | |
| SCHEMBL25890297 | 0.70 | PREP (0.77) | FAPPREPDPP8DPP9DPP4 | |
| SCHEMBL18084196 | 0.69 | FAP (0.71) | FAPPREPDPP8DPP9DPP4 | |
| SCHEMBL25896315 | 0.69 | FAP (0.61) | FAPPREPDPP8DPP9DPP4 | |
| SCHEMBL13347225 | 0.68 | FAP (0.73) | FAPPREPDPP8DPP9DPP4 | |
| SCHEMBL8286524 | 0.68 | FAP (0.73) | FAPPREPDPP8DPP9DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642188-A | Radiopharmaceuticals based on ((R) -1- ((6-hydrazinonicotinyl) -D-alanyl) pyrrolidin-2-yl) boronic acid (HYNIC-IFAP) for detection of fibroblast activation protein overexpression | 国家核研究所 | 2024-03-01 | — | — | CN | disclosed |
| CN-117642188-A | Radiopharmaceuticals based on ((R) -1- ((6-hydrazinonicotinyl) -D-alanyl) pyrrolidin-2-yl) boronic acid (HYNIC-IFAP) for detection of fibroblast activation protein overexpression | 国家核研究所 | 2024-03-01 | — | — | CN | disclosed |
| CN-117642188-A | Radiopharmaceuticals based on ((R) -1- ((6-hydrazinonicotinyl) -D-alanyl) pyrrolidin-2-yl) boronic acid (HYNIC-IFAP) for detection of fibroblast activation protein overexpression | 国家核研究所 | 2024-03-01 | — | — | CN | disclosed |