Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30806978 | 0.84 | BRPF1 (0.49) | RXFP1MEN1KMT2ABRPF1RAB9A | |
| SCHEMBL27195708 | 0.82 | CACNA1H (0.51) | KMT2ARAB9AROCK1SMN1; SMN2POLB | |
| SCHEMBL27195785 | 0.80 | LMNA (0.46) | — | |
| SCHEMBL9132797 | 0.77 | RXFP1 (0.58) | RXFP1MEN1KMT2ABRPF1MAPT | |
| SCHEMBL30806906 | 0.75 | TRPV1 (0.51) | RXFP1ROCK1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL27195733 | 0.74 | TRPV1 (0.59) | MEN1KMT2ARAB9AROCK1SMN1; SMN2 | |
| SCHEMBL11734686 | 0.74 | SMN1; SMN2 (0.52) | MEN1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL10066976 | 0.74 | RXFP1 (0.64) | RXFP1MEN1KMT2ABRPF1RAB9A | |
| SCHEMBL30806836 | 0.73 | PABPC1 (0.54) | RXFP1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL26266333 | 0.73 | NPC1 (0.52) | MEN1KMT2ARAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353712-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2024-04-17 | — | — | EP | disclosed |